The Full Chloroplast Genome of Arabidopsis thaliana Remoted in Korea (Brassicaceae): An Investigation of Intraspecific Variations of the Chloroplast Genome of Korean A. thaliana
Arabidopsis thaliana (L.) Heynh. is a mannequin organism of plant molecular biology. Greater than 1,700 full genome sequences have been sequenced, nonetheless no Korean isolate genomes have been sequenced up to now although many A. thaliana remoted in Japan and China have been sequenced. To know the genetic background of Korean pure A. thaliana (named as 180404IB4),
we offered its full chloroplast genome, which is 154,464 bp extended and has 4 subregions: 85,164 bp of big single copy (LSC) and 17,781 bp of small single copy (SSC) areas are separated by 26,257 bp of inverted repeat (IRs) areas together with 130 genes (85 protein-coding genes, eight rRNAs, and 37 tRNAs). Fifty single nucleotide polymorphisms (SNPs) and 14 insertion and deletions (INDELs) are acknowledged between 180404IB4 and Col0.
Along with, 101 SSRs and 42 extendedSSRs had been acknowledged on the Korean A. thaliana chloroplast genome, indicating an similar variety of SSRs on the remaining 5 chloroplast genomes with a different of sequence variations within the course of the SSR house.
A nucleotide differ evaluation revealed two terribly variable areas on A. thaliana chloroplast genomes. Phylogenetic timber with three further chloroplast genomes of East Asian pure isolates present that Korean and Chinese language language language pure isolates are clustered collectively, whereas two Japanese isolates aren’t clustered, suggesting the necessity for extra investigations of the chloroplast genomes of East Asian isolates.
Loci acknowledged by a genome-wide affiliation research of carotid artery stenosis contained in the eMERGE neighborhood
Carotid artery atherosclerotic illness (CAAD) is a danger topic for stroke. We used a genome-wide affiliation (GWAS) method to hunt out genetic variants related to CAAD in members contained in the digital Medical Knowledge and Genomics (eMERGE) Group.
We acknowledged grownup CAAD conditions with unilateral or bilateral carotid artery stenosis and controls with out proof of stenosis from digital properly being data at eight eMERGE websites. We carried out GWAS with a mannequin adjusting for age, intercourse, research web page, and genetic principal parts of ancestry.
In eMERGE we discovered 1793 CAAD conditions and 17,958 controls. Two loci reached genome-wide significance, on chr6 in LPA (rs10455872, odds ratio [OR] (95% confidence interval [CI]) = 1.50 (1.30-1.73), p = 2.1 × 10-8 ) and on chr7, an intergenic single nucleotide variant (SNV; rs6952610, OR (95% CI) = 1.25 (1.16-1.36), p = 4.3 × 10-8 ). The chr7 affiliation remained essential contained in the presence of the LPA SNV as a covariate. The LPA SNV was furthermore related to coronary coronary coronary coronary heart illness (CHD; 4199 conditions and 11,679 controls) on this research (OR (95% CI) = 1.27 (1.13-1.43), p = 5 × 10-5 ) nonetheless the chr7 SNV was not (OR (95% CI) = 1.03 (0.97-1.09), p = .37).
Each variants replicated in UK Biobank. Elevated lipoprotein(a) concentrations ([Lp(a)]) and LPA variants related to elevated [Lp(a)] have beforehand been related to CAAD and CHD, together with rs10455872. With digital properly being file phenotypes in eMERGE and UKB, we replicated a beforehand acknowledged affiliation and acknowledged a novel locus related to CAAD.
The genetic foundation of pure antibody titers of younger wholesome pigs and relationships with illness resilience
Background: Sickness resilience is the pliability to maintain up effectivity beneath pathogen publicity nonetheless is troublesome to select for on account of breeding populations are raised beneath extreme nicely being. Alternative for resilience requires a trait that is heritable, easy to measure on healthful animals, and genetically correlated with resilience. Pure antibodies (NAb) are important components of the innate immune system and are found to be heritable and associated to sickness susceptibility in dairy cattle and poultry. Our purpose was to investigate NAb and entire IgG in blood of healthful, youthful pigs as potential indicator traits for sickness resilience.
Outcomes: Data have been from Yorkshire x Landrace pigs, with IgG and IgM NAb (Four antigens) and entire IgG measured by ELISA in blood plasma collected ~ 1 week after weaning, earlier to their publicity to a pure polymicrobial downside. Heritability estimates have been lower for IgG NAb (0.12 to 0.24, + 0.05) and for entire IgG (0.19 + 0.05) than for IgM NAb (0.33 to 0.53, + 0.07) nonetheless maternal outcomes have been larger for IgG NAb (0.41 to 0.52, + 0.03) and for entire IgG (0.19 + 0.05) than for IgM NAb (0.00 to 0.10, + 0.04).
Phenotypically, IgM NAb titers have been fairly correlated with each other (widespread 0.60), as have been IgG NAb titers (widespread 0.42), nonetheless correlations between IgM and IgG NAb titers have been weak (widespread 0.09). Phenotypic correlations of entire IgG have been affordable with NAb IgG (widespread 0.46) nonetheless weak with NAb IgM (widespread 0.01).
Estimates of genetic correlations amongst NAb confirmed associated patterns nonetheless with small SE, with estimates averaging 0.76 amongst IgG NAb, 0.63 amongst IgM NAb, 0.17 between IgG and IgM NAb, 0.64 between entire IgG and IgG NAb, and 0.13 between entire IgG and IgM NAb. Phenotypically, pigs that survived had barely elevated ranges of NAb and entire IgG than pigs that died. Genetically, elevated ranges of NAb tended to be associated to higher sickness resilience based totally on lower mortality and fewer parenteral antibiotic therapies. Genome-wide affiliation analyses for NAb titers acknowledged quite a lot of genomic areas, with quite a lot of candidate genes for immune response.
Conclusions: Ranges of NAb in blood of healthful youthful piglets are heritable and potential genetic indicators of resilience to polymicrobial sickness.

Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), APC-Cy7 |
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4-CAC060Hu22-APC-Cy7 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with APC-Cy7. |
Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), Biotinylated |
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4-CAC060Hu22-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with Biotin. |
Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), Cy3 |
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4-CAC060Hu22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with Cy3. |
Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), FITC |
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4-CAC060Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with FITC. |
Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), HRP |
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4-CAC060Hu22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with HRP. |
Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), PE |
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4-CAC060Hu22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with PE. |
Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig) |
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4-CAF548Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1) |
Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), APC |
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4-CAF548Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with APC. |
Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), APC-Cy7 |
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4-CAF548Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with APC-Cy7. |
Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), Biotinylated |
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4-CAF548Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with Biotin. |
Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), Cy3 |
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4-CAF548Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with Cy3. |
Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), FITC |
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4-CAF548Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with FITC. |
Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), HRP |
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4-CAF548Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with HRP. |
Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), PE |
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4-CAF548Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with PE. |
Lamin B1 (LMNB1) Monoclonal Antibody (Human) |
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4-CAF548Hu22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1) |
Lamin B1 (LMNB1) Monoclonal Antibody (Human), APC |
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4-CAF548Hu22-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with APC. |
Lamin B1 (LMNB1) Monoclonal Antibody (Human), APC-Cy7 |
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4-CAF548Hu22-APC-Cy7 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with APC-Cy7. |
Lamin B1 (LMNB1) Monoclonal Antibody (Human), Biotinylated |
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4-CAF548Hu22-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with Biotin. |
Lamin B1 (LMNB1) Monoclonal Antibody (Human), Cy3 |
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4-CAF548Hu22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with Cy3. |
Lamin B1 (LMNB1) Monoclonal Antibody (Human), FITC |
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4-CAF548Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with FITC. |
Lamin B1 (LMNB1) Monoclonal Antibody (Human), HRP |
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4-CAF548Hu22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with HRP. |
Lamin B1 (LMNB1) Monoclonal Antibody (Human), PE |
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4-CAF548Hu22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with PE. |
Lamin A/C (LMNA) Polyclonal Antibody (Human) |
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4-CAF550Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA) |
Lamin A/C (LMNA) Polyclonal Antibody (Human), APC |
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4-CAF550Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with APC. |
Lamin A/C (LMNA) Polyclonal Antibody (Human), APC-Cy7 |
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4-CAF550Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with APC-Cy7. |
Lamin A/C (LMNA) Polyclonal Antibody (Human), Biotinylated |
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4-CAF550Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with Biotin. |
Lamin A/C (LMNA) Polyclonal Antibody (Human), Cy3 |
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4-CAF550Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with Cy3. |
Lamin A/C (LMNA) Polyclonal Antibody (Human), FITC |
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4-CAF550Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with FITC. |
Lamin A/C (LMNA) Polyclonal Antibody (Human), HRP |
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4-CAF550Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with HRP. |
Lamin A/C (LMNA) Polyclonal Antibody (Human), PE |
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4-CAF550Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with PE. |
Lamin A/C (LMNA) Monoclonal Antibody (Human) |
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4-CAF550Hu22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA) |
Lamin A/C (LMNA) Monoclonal Antibody (Human), APC |
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4-CAF550Hu22-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with APC. |
Lamin A/C (LMNA) Monoclonal Antibody (Human), APC-Cy7 |
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4-CAF550Hu22-APC-Cy7 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with APC-Cy7. |
Lamin A/C (LMNA) Monoclonal Antibody (Human), Biotinylated |
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4-CAF550Hu22-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with Biotin. |
Lamin A/C (LMNA) Monoclonal Antibody (Human), Cy3 |
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4-CAF550Hu22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with Cy3. |
Lamin A/C (LMNA) Monoclonal Antibody (Human), FITC |
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4-CAF550Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with FITC. |
Lamin A/C (LMNA) Monoclonal Antibody (Human), HRP |
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4-CAF550Hu22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with HRP. |
Lamin A/C (LMNA) Monoclonal Antibody (Human), PE |
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4-CAF550Hu22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with PE. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human) |
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4-CAG369Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), APC |
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4-CAG369Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with APC. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), APC-Cy7 |
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4-CAG369Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with APC-Cy7. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), Biotinylated |
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4-CAG369Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with Biotin. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), Cy3 |
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4-CAG369Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with Cy3. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), FITC |
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4-CAG369Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with FITC. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), HRP |
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4-CAG369Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with HRP. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), PE |
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4-CAG369Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with PE. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human) |
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4-CAG369Hu22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), APC |
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4-CAG369Hu22-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with APC. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), APC-Cy7 |
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4-CAG369Hu22-APC-Cy7 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with APC-Cy7. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), Biotinylated |
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4-CAG369Hu22-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with Biotin. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), Cy3 |
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4-CAG369Hu22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with Cy3. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), FITC |
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4-CAG369Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with FITC. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), HRP |
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4-CAG369Hu22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with HRP. |
ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), PE |
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4-CAG369Hu22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with PE. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human) |
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4-CAG901Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1) |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), APC |
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4-CAG901Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with APC. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), APC-Cy7 |
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4-CAG901Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with APC-Cy7. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), Biotinylated |
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4-CAG901Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with Biotin. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), Cy3 |
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4-CAG901Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with Cy3. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), FITC |
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4-CAG901Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with FITC. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), HRP |
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4-CAG901Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with HRP. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), PE |
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4-CAG901Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with PE. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human) |
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4-CAG901Hu22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1) |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), APC |
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4-CAG901Hu22-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with APC. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), APC-Cy7 |
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4-CAG901Hu22-APC-Cy7 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with APC-Cy7. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), Biotinylated |
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4-CAG901Hu22-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with Biotin. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), Cy3 |
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4-CAG901Hu22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with Cy3. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), FITC |
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4-CAG901Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with FITC. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), HRP |
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4-CAG901Hu22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with HRP. |
Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), PE |
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4-CAG901Hu22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with PE. |
Human Angiotensin II (AngII) CLIA Kit |
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4-CCA005Hu | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human Angiotensin II (AngII)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids |
Human Glycated Hemoglobin A1c (HbA1c) CLIA Kit |
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4-CCA190Hu | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human Glycated Hemoglobin A1c (HbA1c)serum, plasma and erythrocyte lysates |
Human Anti-Mullerian Hormone (AMH) CLIA Kit |
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4-CCA228Hu | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human Anti-Mullerian Hormone (AMH)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
General Bovine Serum Albumin (BSA) CLIA Kit |
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4-CCA248Ge | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of General Bovine Serum Albumin (BSA)Serum, plasma and other biological fluids |
Cattle Substance P (SP) CLIA Kit |
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4-CCA393Bo | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Cattle Substance P (SP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids |
Dog Substance P (SP) CLIA Kit |
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4-CCA393Ca | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Dog Substance P (SP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids |
Guinea pig Substance P (SP) CLIA Kit |
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4-CCA393Gu | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Guinea pig Substance P (SP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids |
Human Substance P (SP) CLIA Kit |
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4-CCA393Hu | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human Substance P (SP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
Mouse Substance P (SP) CLIA Kit |
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4-CCA393Mu | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Mouse Substance P (SP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids |
Rat Substance P (SP) CLIA Kit |
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4-CCA393Ra | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Rat Substance P (SP)serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids |
General Dehydroepiandrosterone (DHEA) CLIA Kit |
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4-CCA398Ge | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of General Dehydroepiandrosterone (DHEA)serum, plasma and other biological fluids |
ELISA Kit for Luteinizing Hormone (LH) |
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4-CCA441Mu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Luteinizing Hormone (LH) in samples from Serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
Rat Luteinizing Hormone (LH) CLIA Kit |
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4-CCA441Ra | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Rat Luteinizing Hormone (LH)serum, plasma and other biological fluids |
Human C-Peptide (CP) CLIA Kit |
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4-CCA447Hu | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human C-Peptide (CP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids |
Rat C-Peptide (CP) CLIA Kit |
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4-CCA447Ra | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Rat C-Peptide (CP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids |
Human Insulin (INS) CLIA Kit |
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4-CCA448Hu | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human Insulin (INS)Serum, plasma, cell culture supernates and other biological fluids |
Rat Insulin (INS) CLIA Kit |
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4-CCA448Ra | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of Rat Insulin (INS)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids |
General Thyroxine (T4) CLIA Kit |
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4-CCA452Ge | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of General Thyroxine (T4)Serum, plasma and other biological fluids |
General Triiodothyronine (T3) CLIA Kit |
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4-CCA453Ge | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of General Triiodothyronine (T3)Serum, plasma and other biological fluids |
General Estriol (E3) CLIA Kit |
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4-CCA455Ge | Cloud-Clone |
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Description: Competitive Inhibition chemiluminescent immunoassay for detection of General Estriol (E3)Serum, plasma and other biological fluids |
Affiliation analysis of the surfactant protein-C gene to childhood bronchial bronchial asthma
Objectives: This analysis targets to clarify the molecular variability throughout the SFTPC gene in a childhood persistent respiratory sickness, bronchial bronchial asthma, throughout the Tunisian inhabitants and to determine the implications based totally on a case-control analysis of p.Thr138Asn (T138N) and p.Ser186Asn (S186N) variants.
Methods: We used direct sequencing for the genotyping of the SFTPC gene inside 101 asthmatic kids. The analysis of T138N and S186N variants in 110 controls is carried out by the PCR-RFLP technique. Outcomes: The molecular analysis revealed 26 variants along with 24 intronic variations and a pair of exonic variations (T138N and S186N) with respective frequencies of 16.8% and 18.3%. We carried out a case-control analysis of the two acknowledged exonic
variations. A particular genotypic and allelic distribution between the two groups was well-known. Solely the T138N polymorphism confirmed a significant affiliation with bronchial bronchial asthma sickness (p < 10-3).
Statistical analysis elaborated Four haplotypes with the subsequent frequencies in victims vs controls: 138Thr-186Ser (79.5% vs 57.6%), 138Thr-186Asn (3.7% vs 7.8%), 138Asn-186Thr (2.2% vs 20.2%) and 138Asn-186Asn (14.6% vs 14.4%).
A serious distinction (p < 10-3) was highlighted in haplotype distribution. The 138Asn-186Ser (OR [95%CI] = 0.14[0.04-0.54], p = 0.004, R2=0.93) and 138Thr-186Asn (OR [95%CI] = 0.35[0.12-0.54], p = 0.047, R2=0.88) haplotypes confirmed a harmful affiliation with bronchial bronchial asthma which might signify a defending situation in opposition to the sickness.
Conclusion: In Tunisia, this work constitutes the first report throughout the SFTPC gene and highlights the genetic variability of the SFTPC gene in bronchial bronchial asthma. Because of this reality, the case-controls analysis may be useful throughout the analysis of surfactant proteins dysfunction in persistent respiratory sickness at an early age.